Free Radical Scavenging Activities of Lophocereus schottii (Engelmann)
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Antioxidant activity, phenolic compounds, Lophocereus schottii,Abstract
The antioxidant activity of methanol extract of Lophocereus schottii was determined with three different tests: 1,1-diphenyl-2-
picrylhydrazyl radical (DPPH) scavenging; trolox equivalent antioxidant capacity (TEAC); and ferric reducing antioxidant power
(FRAP). The extract showed significant activities in all antioxidant assays, in DPPH radical scavenging assay the EC50 value
was found to be 132.6 μg/ml while catequin had the EC50 value 111.2 μg/ml. Phenolic and flavonoid contents of the extract also
determined and the values were 73 mg (gallic acid equivalent/1 g extract) and 5 mg (catechin equivalent/1 g extract). This finding
indicated that crude extract of L. schottii was a starting material for the isolation of compound(s) with effective activities as
radical’s scavengers.