In silico Designing of Biofilm-associated Protein (Bap) producing of Acinetobacter baumannii

Biofilm-associated Protein (Bap) of Acinetobacter baumannii

Abstract

Acinetobacter baumannii is a significant source of nosocomial infections worldwide. A. baumannii surface protein, commonly known as biofilm associated protein (Bap), is involved in biofilm formation. Several web servers have been used to facilitate the prediction and design of (Bap) for A. baumannii. The results that have been obtained from some servers that have been used in this study were gave a poor and good quality of prediction. SWISS MODEL server gave more promising results. Validation was done for the model study by using QMEAN score and ProSA server. 3D Refine and Mod Refiner were used for model refinement. Finally, ProSA server has been used in order to revalidate the model.